abstract：:Physicians dealing with sexual dysfunction (SD) must consider the psychological and behavioral aspects of their patient's diagnosis and management, as well as organic causes and risk factors. Integrating sex therapy and other psychological techniques into their office practice will improve effectiveness in treating SD...

journal_title：International journal of impotence research

authors： Perelman MA

更新日期：2003-10-01 00:00:00

abstract：:Creation of a neophallus in cases of loss of the penis or female to male trans-sexual is a challenge. The forearm flap is the most popular method used. A penile implant may be placed at the original procedure or at a later date to provide support for intercourse. The hydraulic nondistally expanding types provide the b...

journal_title：International journal of impotence research

authors： Mulcahy JJ

更新日期：2003-10-01 00:00:00

abstract：:The association between different antihypertensive drugs and erectile dysfunction (ED) was examined in a cohort of type II diabetes patients identified in the UK General Practice Research Database (GPRD). The GPRD contains details of diagnoses, prescribing, investigations, risk factors, outcomes, and hospital referral...

journal_title：International journal of impotence research

authors： Blumentals WA,Brown RR,Gomez-Caminero A

更新日期：2003-10-01 00:00:00

abstract：:Erectile dysfunction (ED), generally associated with reduced sexual desire and sometimes with orgasmic or ejaculatory dysfunction, is the major revealing symptom of hyperprolactinemia (HPRL) in men, a condition that should not be neglected since many cases result from pituitary tumors, likely to result in serious comp...

journal_title：International journal of impotence research

authors： Buvat J

更新日期：2003-10-01 00:00:00

abstract：:We evaluated the prevalence of erectile dysfunction (ED) in a cross-sectional community-based random sample of Egyptian men. ED was correlated with the socioeconomic status, risk factors and quality of life. Married men in Ismailia province were interviewed at home. Data were processed for 805 men with mean age of 43....

journal_title：International journal of impotence research

authors： Seyam RM,Albakry A,Ghobish A,Arif H,Dandash K,Rashwan H

更新日期：2003-08-01 00:00:00

abstract：:Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by parkinsonism and cerebellar, autonomic, urinary, and/or pyramidal dysfunction. Urinary and erectile dysfunction (ED) symptoms are prominent early features in men with MSA. Autonomic failure, considered until recently to be the ca...

journal_title：International journal of impotence research

authors： Kirchhof K,Apostolidis AN,Mathias CJ,Fowler CJ

更新日期：2003-08-01 00:00:00

abstract：:We evaluated spontaneous tumescence after penile prostheses implantation in a retrospective study. A total of 32 patients with three-piece hydraulic implants (17 Mentor Alpha I, 15 AMS Ultrex Plus) were enrolled. Consultation, personal interviews and questionnaires for both the patients and their partners provided the...

journal_title：International journal of impotence research

authors： Manning M,Martínez FJ,Alken P,Jünemann KP

更新日期：2003-06-01 00:00:00

abstract：:Sildenafil is one of two oral drugs approved for first-line treatment of erectile dysfunction (ED). Anecdotally, some young healthy men who wish to enhance their sexual performance are requesting or abusing sildenafil. In this randomized double-blind, placebo-controlled clinical study, we investigated the effect of si...

journal_title：International journal of impotence research

authors： Mondaini N,Ponchietti R,Muir GH,Montorsi F,Di Loro F,Lombardi G,Rizzo M

更新日期：2003-06-01 00:00:00

abstract：:Anxiety plays a major role in the development of the problems associated with erectile dysfunction (ED). Psychological and behavioural responses to ED can lead to a vicious cycle of increased uneasiness, distance and conflicts. This in turn leads to a lower frequency of sexual encounters, less time spent together and ...

journal_title：International journal of impotence research

authors： Hedon F

更新日期：2003-04-01 00:00:00

abstract：:The objective of this study was to investigate the predictive validity of the Dutch translation of the Golombok Rust Inventory of Sexual Satisfaction (GRISS) for the presence of clinically relevant sexual dysfunctions and patient's need of help. A total of 57 male urological outpatients (age 50.7+/-13.2 y; range 27-77...

journal_title：International journal of impotence research

authors： van Lankveld JJ,van Koeveringe GA

更新日期：2003-04-01 00:00:00

abstract：:A total of 76 male patients on renal replacement therapy (RRT) were investigated. Erectile dysfunction (ED) was defined as insufficient erection during visual erotic stimulation (VES) or during sleep as measured with Rigiscan and Erectiometer. Data on medical history, physical examination, and laboratory variables wer...

journal_title：International journal of impotence research

authors： Diemont WL,Hendriks JC,Lemmens WA,Langen Hv,Berden JH,Meuleman EJ

更新日期：2003-02-01 00:00:00

abstract：:Isometric tension measurement using a selective Rho-kinase inhibitor (+)- (R)-trans4-(1-aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide (Y-27632) and a selective myosin light chain kinase (MLCK) inhibitor 1-(5-iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML7) were used in rabbit clitoral caver...

journal_title：International journal of impotence research

authors： Park JK,Lee SO,Kim YG,Kim SH,Koh GY,Cho KW

更新日期：2002-12-01 00:00:00

abstract：:New Zealand white rabbit cavernosal smooth muscle strips (n=6) were mounted in organ baths. Relaxations to nitric oxide (10(-7)-10(-4) mol/l) were measured and the same procedure was repeated on strips from rabbits 6 months after alloxan-induced diabetes (n=6). Transverse cavernosal sections were obtained from the sam...

journal_title：International journal of impotence research

authors： Sullivan ME,Mumtaz FH,Dashwood MR,Thompson CS,Naseem KM,Bruckdorfer KR,Mikhailidis DP,Morgan RJ

更新日期：2002-12-01 00:00:00

abstract：:Peyronie's disease is a common malady affecting men mostly between the ages of 40 and 60. When penile curvature and erectile softening are present and the erectile dysfunction does not respond to Viagra a penile implant will strengthen and usually straighten the penis. If curvature persists after implant placement 'mo...

journal_title：International journal of impotence research

authors： Mulcahy JJ,Wilson SK

更新日期：2002-10-01 00:00:00

abstract：:Nitric oxide (NO) is an important mediator in the cavernosal smooth muscle relaxation that causes erections. The purpose of this study was to examine the existence, distribution and phosphorylation stage of two recently discovered key enzymes for NO regulation in human cavernosal tissue, the MAP Kinase 1/2 (Erk 1/2) a...

journal_title：International journal of impotence research

authors： Sommer F,Klotz T,Steinritz D,Schmidt A,Addicks K,Engelmann U,Bloch W

更新日期：2002-08-01 00:00:00

abstract：:Development and maintenance of penile erection requires the relaxation of the smooth muscle cells in the cavernous bodies and is essentially mediated by nitric oxide (NO). The penile flaccid state is conversely maintained by the alpha adrenergic neuroeffector system and by other vasoconstrictors, such as endothelin-1 ...

journal_title：International journal of impotence research

authors： Filippi S,Luconi M,Granchi S,Natali A,Tozzi P,Forti G,Ledda F,Maggi M

更新日期：2002-08-01 00:00:00

abstract：:The objective of this study is to investigate whether the L-arginine/nitric oxide pathway is involved in the neurotransmission of paraventricular nucleus of hypothalamus (PVN) activation-induced penile erection in the rat. Male adult Sprague-Dawley rats anesthetized with pentobarbital were used. The femoral artery was...

journal_title：International journal of impotence research

authors： Chen KK,Chang LS

更新日期：2002-06-01 00:00:00

abstract：:From the files of the outpatient urology department 44 men with ED had undergone both psychophysiological diagnostic screening (PDS, VSS, VSS+VIB, ICI+VSS+VIB) and color Doppler sonography testing (CDS, including VSS). PDS was carried out by one medical physiologist, CDS by one urologist. The diagnoses reached could b...

journal_title：International journal of impotence research

authors： Slob AK,Cornelissen S,Dohle GR,Gijs L,van der Werff ten Bosch JJ

更新日期：2002-06-01 00:00:00

abstract：:The isometric tension measurement and in vitro autoradiography were used in clitoral cavernosum smooth muscle (CSM). Angiotensin ANG III, ANG IV, ANG II and ANG I induced contractions in clitoral CSM strips. ANG III and ANG I- induced contraction was five times less active than ANG II, whereas ANG IV-induced contracti...

journal_title：International journal of impotence research

authors： Park JK,Kim SZ,Kim JU,Kim YG,Kim SM,Cho KW

更新日期：2002-04-01 00:00:00

abstract：:In several studies we have recently demonstrated that orgasm induces prolactin secretion in healthy males and females. This suggests that prolactin may form a feedback regulator of the refractory period following orgasm. To examine this position we investigated the prolactin response of a healthy multi-orgasmic male s...

journal_title：International journal of impotence research

authors： Haake P,Exton MS,Haverkamp J,Krämer M,Leygraf N,Hartmann U,Schedlowski M,Krueger TH

更新日期：2002-04-01 00:00:00

abstract：:Penile erection is a vascular phenomenon that results from smooth muscle relaxation, arterial dilation and venous restriction. The atherosclerosis of the penis that occurs with aging causes a decrease in penile oxygen tension. A reduction of smooth muscle cells has been demonstrated in relation with this change in oxy...

journal_title：International journal of impotence research

authors： Wespes E

更新日期：2002-02-01 00:00:00

abstract：:Research in the field of erectile function and dysfunction has continued to expand rapidly. Based on the information available, some directions for future erectile dysfunction therapies can be identified. The first direction is improvement of current therapeutic principles. A second generation of orally active phospho...

journal_title：International journal of impotence research

authors： Andersson KE,Hedlund P

更新日期：2002-02-01 00:00:00

abstract：:In order to assess the effectiveness of sildenafil under routine conditions of use in primary care settings and to evaluate its impact on patient's life satisfaction and partner's satisfaction with treatment for erectile dysfunction (ED), an open, multicentre, observational, prospective study was designed in which 281...

journal_title：International journal of impotence research

authors： Gil A,Martínez E,Oyagüez I,Palacios G,Rejas J

更新日期：2001-12-01 00:00:00

abstract：:Between December 1996 and December 1998, 79 inflatable penile implant insertions have been performed at our institution by a single surgeon. The objective of this analysis was to compare our in-patient and out-patient experience with penile prosthesis insertion with respect to ease of performance and complication prof...

journal_title：International journal of impotence research

authors： Mulhall JP,Bloom K

更新日期：2001-10-01 00:00:00

abstract：:Despite extensive research into the toxicity of bisphenol A (BPA), no report of its effect on erectile function exists. We performed this study to investigate the effect of BPA on erectile function. New Zealand white rabbits were treated intraperitoneally with 150 mg/kg of BPA every other day for 12 days (cumulative d...

journal_title：International journal of impotence research

authors： Moon DG,Sung DJ,Kim YS,Cheon J,Kim JJ

更新日期：2001-10-01 00:00:00

abstract：:Experimental models to study the effect of agents on penile erection usually include electrical stimulation of peripheral nerves in anesthetized animals combined with systemic or intracavernous injection of drugs. The objective of this study was to demonstrate that conscious rabbits can be used as a simple and quantit...

journal_title：International journal of impotence research

authors： Bischoff E,Schneider K

更新日期：2001-08-01 00:00:00

abstract：:The clinical profile for apomorphine sublingual (SL), a new centrally active agent for the management of the erectile dysfunction (ED) patient, is described in this article. Apomorphine SL is shown to be rapid in onset (71% of patients within 20 min) with a consistent, predictable response that is independent of sever...

journal_title：International journal of impotence research

authors： Heaton JP

更新日期：2001-08-01 00:00:00

abstract：:The aim of this work was to characterize the effect of experimental diabetes on neurotransmission in rat vagina. Female Sprague-Dawley rats were divided into two groups: non-diabetic controls (NDM, n=38) and diabetics (DM, n=38). DM was produced by intraperitoneal injection of streptozotocin. Eight weeks later the ani...

journal_title：International journal of impotence research

authors： Giraldi A,Persson K,Werkström V,Alm P,Wagner G,Andersson KE

更新日期：2001-04-01 00:00:00

abstract：:Considering the presence of dopaminergic receptors in the lumbosacral spinal cord, we tested whether apomorphine could exert a proerectile effect by acting at the spinal level. Intracavernous (ICP) and blood pressures (BP) were measured in anesthetized rats. ICP rises were quantified (duration, percentage of ICPmaximu...

journal_title：International journal of impotence research

authors： Giuliano F,Allard J,Rampin O,Droupy S,Benoit G,Alexandre L,Bernabe J

更新日期：2001-04-01 00:00:00

abstract：:This paper: (i) describes the worldwide prevalence of erectile dysfunction (ED); (ii) presents age-specific incidence rates for ED in the US; (iii) summarizes some key epidemiologic correlates of ED in the general population; and (iv) considers the possibility that ED may be a biobehavioral marker (sentinel event) of ...

journal_title：International journal of impotence research

authors： McKinlay JB

更新日期：2000-10-01 00:00:00

abstract：:Apomorphine SL (TAP Holdings, Deerfield, IL) is a centrally acting treatment for erectile dysfunction (ED) that has been undergoing phase III trials. Over 3000 men have received apomorphine SL and over 75,000 doses have been taken. In the first three phase III parallel arm cross-over double-blind studies 854 patients ...

journal_title：International journal of impotence research

authors： Heaton JP

更新日期：2000-10-01 00:00:00

abstract：:Peyronie's disease (PD) is a condition characterized by localized and often progressive fibrosis and scarring of the penis. This condition has an unknown etiology although several hypotheses have been proposed. These include traumatic, immunologic and genetic causes. We studied the genetics and immunology of PD using ...

journal_title：International journal of impotence research

authors： Noss MB,Day NS,Christ GJ,Melman A

更新日期：2000-10-01 00:00:00

abstract：:A concise, reliable means of assessing erectile dysfunction (ED) in large, multidisciplinary population-based studies is needed. A single, direct question for self-assessed ED was assessed in the population-based sample of the Massachusetts Male Aging Study (MMAS). Of the 1156 respondents to the 1995-97 MMAS follow-up...

journal_title：International journal of impotence research

authors： Derby CA,Araujo AB,Johannes CB,Feldman HA,McKinlay JB

更新日期：2000-08-01 00:00:00

abstract：:Radical retropubic prostatectomy (RRP) is an important cause of iatrogenic erectile dysfunction (ED). While sildenafil has been widely used since its introduction as a new treatment option for ED, its efficacy in post-RRP patients has not been extensively studied. We retrospectively compared the efficacy of sildenafil...

journal_title：International journal of impotence research

authors： Blander DS,Sanchez-Ortiz RF,Wein AJ,Broderick GA

更新日期：2000-06-01 00:00:00

abstract：:Hypogonadotropic patients may visit pediatricians, general practitioners, endocrinologists or urologists, presenting with microphallus, cryptochidism or pubertas tarda and delayed bone maturation. Congenital hypogonadotropic hypogonadism is characterized, apart from small testes, by the constellation of low serum leve...

journal_title：International journal of impotence research

authors： John H,Schmid C

更新日期：2000-04-01 00:00:00

abstract：:Penile erection is completely dependent on commands from the central nervous system. Spinal centers controlling penile erection are located in the thoracolumbar and lumbosacral spinal cord. These centers are activated by information from the periphery and supraspinal nuclei so as to elicit penile erection in a variety...

journal_title：International journal of impotence research

authors： Giuliano F,Rampin O

更新日期：2000-03-01 00:00:00

abstract：:The sympathetic nervous system is important for penile function: it mediates detumescence and may contribute to the maintenance of the penis in a non-erect state. The sympathetic preganglionic neurons are found in the intermediolateral gray matter of the spinal cord. Postganglionic neurons are located to the sympathet...

journal_title：International journal of impotence research

authors： Andersson KE,Hedlund P,Alm P

更新日期：2000-03-01 00:00:00

abstract：:This discussion summarizes the potential differences in physiologically and pharmacologically induced erections and highlights the possible differences in the pathways facilitated by oral versus intracavernosal agents in penile erection. Oral agents act in conjunction with sexual stimulation either increasing corporal...

journal_title：International journal of impotence research

authors： Lue T,Goldstein I I,Traish A

更新日期：2000-03-01 00:00:00

abstract：:During penile pharmacotesting, anxiety may overcome complete smooth muscle relaxation and lead to false positive diagnosis of organic male erectile dysfunction (ED). We tested the efficacy and safety of re-dosing of PGE1 alone versus combination of PGE, and the alpha1,2-blocker phentolamine (PHE) to improve an incompl...

journal_title：International journal of impotence research

authors： Aversa A,Bonifacio V,Moretti C,Frajese G,Fabbri A

更新日期：2000-02-01 00:00:00

abstract：:Both RigiScan and the Snap Gauge band devices are used to objectively measure penile rigidity. The Snap Gauge band is the more simple and inexpensive of the two techniques. We investigated the correlation between the results obtained by both devices in order to evaluate whether the Snap Gauge band could be employed as...

journal_title：International journal of impotence research

authors： Chen J,Greenstein A,Sofer M,Matzkin H

更新日期：1999-12-01 00:00:00